Structure of Lipoproteins: Covalently Bound Fatty Acids

作者：Waldo R. Fisher, Samuel Gurin · 发表于：Science · 年份：1964 · DOI：10.1126/science.143.3604.362 · 被引用次数：39 · 研究领域：Cancer, Lipids, and Metabolism、Cholesterol and Lipid Metabolism、Lipid metabolism and biosynthesis

Plasma lipoproteins, extensively extracted with organic solvents, contain small quantities of firmly bound long-chain fatty acids. Upon enzymatic digestion of the protein and partial purification of the resulting peptides, fatty acids are found associated with a peptide fraction which contains organic phosphate. The nature of the linkage between the fatty acid and peptide is unknown.