Drimane Sesquiterpenoids from the Mangrove-Derived Fungus Aspergillus ustus

作者：Huinan Zhou, Tianjiao Zhu, Shengxin Cai, Qianqun Gu, Dehai Li · 发表于：Chemical and Pharmaceutical Bulletin · 年份：2011 · DOI：10.1248/cpb.59.762 · 被引用次数：58 · 研究领域：Marine Sponges and Natural Products、Microbial Natural Products and Biosynthesis、Phytochemical compounds biological activities

Five new drimane sesquiterpenes (1-5) together with 14 known analogues (6-19) were isolated from laboratory cultures of a mangrove-derived fungus Aspergillus ustus. Their structures were established by spectroscopic methods and antitumor activities were evaluated by sulforhodamine B (SRB) and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) methods.