Is there another way to take account of noncompliance in randomized controlled trials?

作者：Catherine Hewitt · 发表于：Canadian Medical Association Journal · 年份：2006 · DOI：10.1503/cmaj.051625 · 被引用次数：138 · 研究领域：Health Systems, Economic Evaluations, Quality of Life、Colorectal Cancer Screening and Detection、Statistical Methods in Clinical Trials

Noncompliance is an important issue in the design and conduct of randomized controlled trials (RCTs). It arises when participants do not receive the treatment or intervention to which they were randomly allocated. For example, some participants invited to go through a screening program may not