Thirty days complication rate following surgery performed for deep‐brain‐stimulation

作者：Jürgen Voges, Rüdiger Hilker, Kai Bötzel, Karl Kiening, Manja Kloß, Andreas Kupsch, Alfons Schnitzler, Gerd‐Helge Schneider, U. Steude, Günther Deuschl, M. Pinsker · 发表于：Movement Disorders · 年份：2007 · DOI：10.1002/mds.21481 · 被引用次数：204 · 研究领域：Neurological disorders and treatments、Parkinson's Disease Mechanisms and Treatments、Botulinum Toxin and Related Neurological Disorders

Serious adverse events (SAEs) during the first 30 postoperative days after stereotactic surgery for Deep-Brain-Stimulation performed in 1,183 patients were retrospectively collected from five German stereotactic centers. The mortality rate was 0.4% and causes for death were pneumonia, pulmonary embolism, hepatopathy, and a case of complicated multiple sclerosis. The permanent surgical morbidity rate was 1%. The most frequently observed SAEs were intracranial hemorrhage (2.2%) and pneumonia (0.6%). Skin infection occurred in 5 of 1,183 patients (0.4%). Surgical complications caused secondary AEs (e.g. pneumonia) preferentially in older patients and in patients treated for Parkinson's disease (PD). Complication rates did not differ among the five centers.