Design and synthesis of a highly selective fluorescent turn-on probe for thiol bioimaging in living cells

作者：Xin Li, Shijing Qian, Qiaojun He, Bo Yang, Jia Li, Yongzhou Hu · 发表于：Organic & Biomolecular Chemistry · 年份：2010 · DOI：10.1039/c004344c · 被引用次数：118 · 研究领域：Sulfur Compounds in Biology、Molecular Sensors and Ion Detection、Nanoplatforms for cancer theranostics

A new fluorescent turn-on probe for the rapid optical sensing of thiols has been designed and synthesized. The probe displays high on/off signal ratios and high selectivity towards thiols. The potential of the probe as a biosensor for thiols was demonstrated by imaging of thiols in living cells.