Role of Anthocyanidin Reductase, Encoded by BANYULS in Plant Flavonoid Biosynthesis

作者：De‐Yu Xie, Shashi B. Sharma, Nancy L. Paiva, Daneel Ferreira, Richard Arthur Dixon · 发表于：Science · 年份：2003 · DOI：10.1126/science.1078540 · 被引用次数：767 · 研究领域：Plant Gene Expression Analysis、Plant biochemistry and biosynthesis、Fermentation and Sensory Analysis

Condensed tannins (CTs) are flavonoid oligomers, many of which have beneficial effects on animal and human health. The flavanol (-)-epicatechin is a component of many CTs and contributes to flavor and astringency in tea and wine. We show that the BANYULS (BAN) genes from Arabidopsis thaliana and Medicago truncatula encode anthocyanidin reductase, which converts anthocyanidins to their corresponding 2,3-cis-flavan-3-ols. Ectopic expression of BAN in tobacco flower petals and Arabidopsis leaves results in loss of anthocyanins and accumulation of CTs.