Depression as a risk factor for cardiac events in established coronary heart disease: A review of possible mechanisms

作者：Robert M. Carney, Kenneth E. Freedland, Michael W. Rich, Allan S. Jaffe · 发表于：Annals of Behavioral Medicine · 年份：1995 · DOI：10.1007/bf02895063 · 被引用次数：261 · 研究领域：Cardiac Health and Mental Health、Heart Rate Variability and Autonomic Control、Heart rate and cardiovascular health

Depression is highly prevalent in patients with coronary heart disease (CHD) and is associated with excess medical morbidity and mortality. This article reviews the mechanisms which may mediate the relationship between depression and cardiac events in these patients. Research in this area is at an early stage of development. However, there is evidence that altered autonomic tone, smoking, hypertension, and, at least in older patients, poor adherence to the cardiac treatment regimen may be responsible for the adverse cardiac effects of depression.