Palladium-Catalyzed Formation of Diaryl Ethers from Aryl Bromides. Electron Poor Phosphines enhance Reaction Yields

作者：Grace Mann, John F. Hartwig · 发表于：Tetrahedron Letters · 年份：1997 · DOI：10.1016/s0040-4039(97)10175-7 · 被引用次数：126 · 研究领域：Catalytic Cross-Coupling Reactions、Catalytic C–H Functionalization Methods、Sulfur-Based Synthesis Techniques

Aryl bromides were converted to diaryl ethers with sodium aryl oxides in the presence of catalytic amounts of Pd(DBA)2 and DPPF. Isolated yields of over 90% were achieved in reactions with electron deficient aryl bromides and electron rich sodium aryl oxides. Electron poor DPPF derivatives led to increased reaction yields. © 1997 Elsevier Science Ltd.