Four New Jacaranone Analogs from the Fruits of a Beibu Gulf Mangrove Avicennia marina

作者：Xiang‐Xi Yi, Yong Chen, Yong Chen, Wen‐Pei Xie, Mingben Xu, Yinning Chen, Yinning Chen, Cheng‐Hai Gao, Riming Huang · 发表于：Marine Drugs · 年份：2014 · DOI：10.3390/md12052515 · 被引用次数：24 · 研究领域：Marine Sponges and Natural Products、Seaweed-derived Bioactive Compounds、Synthesis of Organic Compounds

Four new jacaranone analogs, marinoids F-I (1-4), were isolated from the fruits of a Beibu Gulf mangrove Avicennia marina. The structures were elucidated based on analysis of spectroscopic data. Marinoids F and G are shown to be diastereoisomers of chlorocornoside, a new halogen containing marine secondary metabolite. The antioxidant activity of the isolates was evaluated using a cellular antioxidant assay, and 4 showed good antioxidant activity (EC₅₀ = 26 μM).