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The centrifugal microfluidic Bio-Disk platform

作者:Jens Ducrée, S. Haeberle, S. Lutz, Sarah Pausch, Felix von Stetten, Roland Zengerle · 发表于:Journal of Micromechanics and Microengineering · 年份:2007 · DOI:10.1088/0960-1317/17/7/s07 · 被引用次数:415 · 研究领域:Microfluidic and Bio-sensing Technologies、Microfluidic and Capillary Electrophoresis Applications、3D Printing in Biomedical Research

This paper reviews the centrifugal 'Bio-Disk' platform which is based on rotationally controlled, multi-scale liquid handling to fully integrate and automate complex analysis and synthesis protocols in the life sciences. The platform offers the crucial ingredients for a rapid development of applications: a coherent library of fluidic unit operations, a device technology for actuation, liquid interfacing and detection as well as a developer toolbox providing experimental testing, rapid prototyping and simulation capabilities. Various applications in the fields of life science, in vitro diagnostics and micro-process engineering are demonstrated.