Differentiation of Epidermis and Epidermal Derivatives

作者：Norman K. Wessells · 发表于：New England Journal of Medicine · 年份：1967 · DOI：10.1056/nejm196707062770107 · 被引用次数：100 · 研究领域：Skin and Cellular Biology Research、melanin and skin pigmentation、Cellular Mechanics and Interactions

THIS paper is a selective and speculative review about some phases of skin biology. One of its purposes is to show how the technics of experimental embryology have been and can be adapted to investigation of the skin. The paper is not intended to be a comprehensive source of information on epidermis and epidermal derivatives, since a seemingly endless number of symposia, monographs and texts fulfill that function.The study of skin and its maturation is intriguing from many points of view. As a tissue with a permanent germinal population that produces differentiating cells, the epidermis provides a model system . . .