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Microfluidic Mixing: A Review

作者:Chia‐Yen Lee, Chin‐Lung Chang, Yaonan Wang, Lung‐Ming Fu · 发表于:International Journal of Molecular Sciences · 年份:2011 · DOI:10.3390/ijms12053263 · 被引用次数:1121 · 研究领域:Microfluidic and Capillary Electrophoresis Applications、Microfluidic and Bio-sensing Technologies、Innovative Microfluidic and Catalytic Techniques Innovation

The aim of microfluidic mixing is to achieve a thorough and rapid mixing of multiple samples in microscale devices. In such devices, sample mixing is essentially achieved by enhancing the diffusion effect between the different species flows. Broadly speaking, microfluidic mixing schemes can be categorized as either "active", where an external energy force is applied to perturb the sample species, or "passive", where the contact area and contact time of the species samples are increased through specially-designed microchannel configurations. Many mixers have been proposed to facilitate this task over the past 10 years. Accordingly, this paper commences by providing a high level overview of the field of microfluidic mixing devices before describing some of the more significant proposals for active and passive mixers.