Fungal products. Part III. Structure of wortmannin and some hydrolysis products

作者：Jake MacMillan, A. E. Vanstone, S. K. Yeboah · 发表于：Journal of the Chemical Society Perkin Transactions 1 · 年份：1972 · DOI：10.1039/p19720002898 · 被引用次数：43 · 研究领域：Microbial Natural Products and Biosynthesis

Structure (II) is proposed for the fungal metabolite, wortmannin. The absolute stereochemistry is deduced except for that at C-1, which remains undefined. The structure of the previously described acid, C21H22O7, obtained by acidic degradation, is determined, together with structures of the products of hydrolysis by potassium carbonate and by potassium hydrogen carbonate.