Mitochondrial Dynamics — Mitochondrial Fission and Fusion in Human Diseases

作者：Stephen L. Archer · 发表于：New England Journal of Medicine · 年份：2013 · DOI：10.1056/nejmra1215233 · 被引用次数：1122 · 研究领域：Mitochondrial Function and Pathology、Metabolism and Genetic Disorders、ATP Synthase and ATPases Research

Mitochondria fuse and divide in response to cell demands and environment. Alterations in mitochondrial dynamics underlie various human diseases, including cancer and neurologic and cardiovascular diseases. Defining the alterations may identify potential therapeutic targets.