Multiple Sclerosis: Clues to its Cause

作者：Labe C. Scheinberg · 发表于：Archives of Neurology · 年份：1974 · DOI：10.1001/archneur.1974.00490380091019 · 被引用次数：31 · 研究领域：SARS-CoV-2 and COVID-19 Research、Multiple Sclerosis Research Studies

This book of 351 pages and with approximately 500 references is a labor of love and is intended for the serious investigator in the field of multiple sclerosis. At the price it is also intended for the affluent neurologist. The focus of the monograph is an epidemiologic study of multiple sclerosis in Israel with an intensive statistical analysis of such features as initial symptom, death rate by clinical types, comparison of multiple sclerosis in Europeans and Afro-Asians in Israel, etc. At times the many tables overwhelm and exhaust the reader as the authors set out meticulously to document their hypothesis, linking household sanitation to multiple sclerosis. The hypothesis itself is finally presented on page 332 and again on the last page: It was speculated that MS is due to an environmental infectious agent-in drinking water. The time of acquisition of the agent is reported as critical: if acquired in