Solid‐phase microtiter radioimmunoassay for detection of the Norwalk strain of acute nonbacterial, epidemic gastroenteritis virus and its antibodies

作者：Harry B. Greenberg, Richard G. Wyatt, J Valdesuso, Anthony R. Kalica, William T. London, Robert M. Chanock, Albert Z. Kapikian · 发表于：Journal of Medical Virology · 年份：1978 · DOI：10.1002/jmv.1890020204 · 被引用次数：163 · 研究领域：Viral gastroenteritis research and epidemiology、Bacteriophages and microbial interactions、Respiratory viral infections research

The development of microtiter solid-phase radioimmunoassays for the detection of Norwalk antigen and its antibody is described. The tests are simple to perform and are sensitive and specific. The test for antigen can be used on crude stool filtrates and suspensions. Both tests are at least as sensitive as immune electron microscopy and more sensitive than immune adherence assay.