Ecto-Enzyme of Granulocytes: 5′-Nucleotidase

作者：Joseph William DePierre, Manfred L. Karnovsky · 发表于：Science · 年份：1974 · DOI：10.1126/science.183.4129.1096 · 被引用次数：107 · 研究领域：Adenosine and Purinergic Signaling、Cancer Research and Treatments、Cytomegalovirus and herpesvirus research

The 5'-nucleotidase of guinea pig polymorphonuclear leukocytes is localized exclusively on the plasma membrane of intact cells. The active site of this enzyme faces the external medium, not the cytoplasm.