Thrombocytopenia in Alcoholics

作者：John Lindenbaum, R. LESLIE HARGROVE · 发表于：Annals of Internal Medicine · 年份：1968 · DOI：10.7326/0003-4819-68-3-526 · 被引用次数：123 · 研究领域：Alcohol Consumption and Health Effects、Liver Disease Diagnosis and Treatment、Alcoholism and Thiamine Deficiency

Ten episodes of thrombocytopenia in five chronic alcoholics with delirium tremens are described. Platelet counts rapidly returned to normal after withdrawal of alcohol with a subsequent thrombocytosis. None of the patients had cirrhosis, splenomegaly, or evidence of folic acid deficiency. Thrombocytopenia recurred in three patients 4 to 8 weeks after discharge from hospital and resumption of ethanol intake. It is postulated that the thrombocytopenia was a direct effect of alcohol intoxication by a mechanism as yet unknown.