The influence of the host on expression of intestinal microbial enzyme activities involved in metabolism of foreign compounds

作者：Christopher B. Cole, R. Fuller, Adrien Mallet, Ian Rowland · 发表于：Journal of Applied Bacteriology · 年份：1985 · DOI：10.1111/j.1365-2672.1985.tb03359.x · 被引用次数：88 · 研究领域：Probiotics and Fermented Foods、Gut microbiota and health、Microbial Metabolites in Food Biotechnology

The activities of four enzymes (beta-glucuronidase, nitrate reductase and nitroreductase) in selected intestinal bacteria (Escherichia coli, Clostridium sp., Streptococcus sp., Bacteroides sp. and Lactobacillus salivarius) were measured after growth in vitro and in vivo. The five strains differed in their activities with Clostridium sp. being the most active for beta-glucosidase, beta-glucuronidase and nitroreductase, and E. coli the most active producer of nitrate reductase. Enzyme activity in vivo tended to be higher than in vitro but there were instances where the comparative activities were reversed.