Polymerization-Induced Self-Assembly of Block Copolymer Nano-objects via RAFT Aqueous Dispersion Polymerization

作者：Nicholas J. Warren, Steven P. Armes · 发表于：Journal of the American Chemical Society · 年份：2014 · DOI：10.1021/ja502843f · 被引用次数：1099 · 研究领域：Advanced Polymer Synthesis and Characterization、Nanoparticle-Based Drug Delivery、Block Copolymer Self-Assembly

In this Perspective, we discuss the recent development of polymerization-induced self-assembly mediated by reversible addition-fragmentation chain transfer (RAFT) aqueous dispersion polymerization. This approach has quickly become a powerful and versatile technique for the synthesis of a wide range of bespoke organic diblock copolymer nano-objects of controllable size, morphology, and surface functionality. Given its potential scalability, such environmentally-friendly formulations are expected to offer many potential applications, such as novel Pickering emulsifiers, efficient microencapsulation vehicles, and sterilizable thermo-responsive hydrogels for the cost-effective long-term storage of mammalian cells.