Microbiota is essential for social development in the mouse

作者：Lieve Desbonnet, Gerard Clarke, Fergus Shanahan, Timothy G. Dinan, John F. Cryan · 发表于：Molecular Psychiatry · 年份：2013 · DOI：10.1038/mp.2013.65 · 被引用次数：873 · 研究领域：Gut microbiota and health、Neuroendocrine regulation and behavior、Infant Health and Development

The microbiota–gut–brain axis is an emerging concept in modern medicine informed by the ability of gut microbiota to alter brain and behaviour. 1 Although some clinical studies have revealed altered gut microbiota composition in patients with neurodevelopmental disorders such as autism, 2 , 3 the specific contributions of microbiota in early life to the development and programming of the various facets of social behaviour has not been investigated.