An Artificial Nanopore for Molecular Sensing

作者：Omar Abdullah Saleh, Lydia L. Sohn · 发表于：Nano Letters · 年份：2002 · DOI：10.1021/nl0255202 · 被引用次数：262 · 研究领域：Nanopore and Nanochannel Transport Studies、Microfluidic and Capillary Electrophoresis Applications、Advanced biosensing and bioanalysis techniques

We have used micromolding techniques to embed a nanoscale pore in PDMS. This novel design allows rapid and reproducible fabrication of pores, is extremely flexible, and can be modified both structurally and chemically for a variety of single-molecule detection applications. We demonstrate the capabilities of the device to sense electronically single DNA molecules.