Non-invasive antidromic neurostimulation: A simple effective method for improving bladder storage

作者：IAN K. WALSH, Trevor J. Thompson, W. G. G. LOUGHRIDGE, Samuel R Johnston, P. F. KEANE, Anthony R. Stone · 发表于：Neurourology and Urodynamics · 年份：2000 · DOI：10.1002/1520-6777(2001)20:1<73::aid-nau9>3.0.co;2-3 · 被引用次数：21 · 研究领域：Urinary Bladder and Prostate Research、Pelvic floor disorders treatments、Migraine and Headache Studies

Patients with intractably diminished bladder storage function are encountered frequently by neurourologists, occasionally requiring reconstructive surgery for appropriate resolution. Although sacral neuromodulation is a recognized effective therapeutic modality, present techniques are technically demanding, invasive, and expensive. This study investigated the effect of non-invasive third sacral nerve (S3) stimulation on bladder activity during filling cystometry. One hundred forty-six patients underwent standard urodynamic filling cystometry that was then immediately repeated. Patients in the study group (n = 74) received antidromic transcutaneous sacral neurostimulation during the second fill and the control group (n = 72) underwent a second fill without neurostimulation. A statistically significant increase in bladder storage capacity without a corresponding rise in detrusor pressure was observed in the neurostimulated patients. This improvement in functional capacity is an encouraging finding that further supports the use of this non-invasive treatment modality in clinical practice.