Membrane glycolipids in stem cells

作者：Robert K. Yu, Yusuke Suzuki, Makoto Yanagisawa · 发表于：FEBS Letters · 年份：2009 · DOI：10.1016/j.febslet.2009.08.026 · 被引用次数：44 · 研究领域：Glycosylation and Glycoproteins Research、Caveolin-1 and cellular processes、Lipid Membrane Structure and Behavior

Stem cells, such as embryonic stem cells, hematopoietic stem cells, neural stem cells, mesenchymal stem cells, and very small embryonic-like stem cells, are undifferentiated cells that are endowed with a high potential for proliferation and the capacity for self-renewal with retention of pluri/multipotency to differentiate into their progenies. Recently, studies regarding the biological functions of glycolipids and cell surface microdomains (caveolae, lipid rafts, or glycolipid-enriched microdomains) in stem cells are emerging. In this review, we introduce the expression patterns of glycolipids and the functional roles of cell surface microdomains in stem cells.