Two New C21 Steroidal Glycosides from the Stems of Cynanchum paniculatum Kitag.

作者：Xin Huang, Aimin Tan, Shibao Yang, Zhang An-yuan, Hua Zhang · 发表于：Helvetica Chimica Acta · 年份：2009 · DOI：10.1002/hlca.200800314 · 被引用次数：7 · 研究领域：Phytochemistry and Bioactive Compounds、Phytochemical compounds biological activities、Natural product bioactivities and synthesis

Abstract magnified image Two new glycosides, (3 β ,8 β ,9 α ,16 α ,17 α )‐14,16 β : 15,20 α :18,20 β ‐triepoxy‐16 α ,17 α ‐dihydroxy‐14‐oxo‐13,14 : 14,15‐disecopregna‐5,13(18)‐dien‐3‐yl α ‐cymaropyranosyl‐(1→4)‐ α ‐digitoxopyranosyl‐(1→4)‐ α ‐oleandropyranoside ( 1 ) and (3 β ,8 β ,9 α ,16 α ,17 α )‐14,16 β : 15,20 α : 18,20 β ‐triepoxy‐16 β : 17 α ‐dihydroxy‐14‐oxo‐13,14 : 14,15‐disecopregna‐5,13(18)‐dien‐3‐yl α ‐oleandropyranosyl‐(1→4)‐ α ‐digitoxopyranosyl‐(1→4)‐ α ‐oleandropyranoside ( 2 ) were isolated from the stems of Cynanchum paniculatum ( Bunge ) Kitag . The structures of the new compounds were elucidated by means of spectral data, including HR‐ESI‐MS, and 1D‐, and 2D‐NMR.