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A catalogue of splice junction sequences

作者:Stephen M. Mount · 发表于:Nucleic Acids Research · 年份:1982 · DOI:10.1093/nar/10.2.459 · 被引用次数:3880 · 研究领域:RNA Research and Splicing、RNA and protein synthesis mechanisms、Fungal and yeast genetics research

Splice junction sequences from a large number of nuclear and viral genes encoding protein have been collected. The sequence CAAG/GTAGAGT was found to be a consensus of 139 exon-intron boundaries (or donor sequences) and (TC)nNCTAG/G was found to be a consensus of 130 intron-exon boundaries (or acceptor sequences). The possible role of splice junction sequences as signals for processing is discussed.