The mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen f4/80: Macrophages of bone and associated connective tissue

作者：David Hume, John Freeman Loutit, Siamon Gordon · 发表于：Journal of Cell Science · 年份：1984 · DOI：10.1242/jcs.66.1.189 · 被引用次数：121 · 研究领域：Cell Adhesion Molecules Research、Bone Metabolism and Diseases、Radiopharmaceutical Chemistry and Applications

The macrophage-specific antigen F4/80 has been localized in adult mouse bone and connective tissue. F4/80 positive cells form the centre of haemopoietic islands, line the periosteal and subendosteal bone surfaces and are a major component of connective tissue and the synovial membrane (presumptive type A cells). F4/80 is absent from fibroblasts, chondrocytes, osteoblasts, osteocytes, osteoclasts and a subpopulation of synovial lining cells (presumptive type B cells).