The association of well-being, productivity and resource use among community-dwelling patients with schizophrenia using atypical antipsychotics

作者：Marco DiBonaventura, Jessica Panish, Debbie Kenworthy, Jan-Samuel Wagner, Riad Dirani · 发表于：Journal of Pharmaceutical Health Services Research · 年份：2010 · DOI：10.1111/j.1759-8893.2010.00033.x · 被引用次数：2 · 研究领域：Schizophrenia research and treatment、Health Systems, Economic Evaluations, Quality of Life、Chronic Disease Management Strategies

The aim of the current study was to examine levels of well-being and productivity and the interrelationships between them in community-dwelling patients with schizophrenia who use atypical antipsychotic medications. A mixed methodology (online and paper surveys) was implemented to recruit patients in the USA over the age of 18 years who were diagnosed with schizophrenia by a healthcare professional and who were able to read and write English. Patients who were currently being treated with an atypical medication and provided well-being data (n = 745) were included in the analyses. Logistic and negative binomial regressions were used to determine the effect of well-being on productivity and resource use. Almost two-thirds of patients taking atypical antipsychotics reported low levels of well-being (63%). After controlling for demographic and patient characteristics, patients with low levels of well-being were significantly less likely to be employed and productive than patients with moderate or high levels of well-being (P < 0.05). Similarly, patients with low levels of well-being were significantly more likely to be hospitalized or visit the emergency room relative to patients with high levels of well-being (P < 0.05). The results suggest that there may be an unmet need among patients with schizophrenia who use atypical antipsychotic medications. Overall levels of well-being were low in these community-dwelling patients. Further, low levels of well-being were found to be signi...