Inhibition of RAF Isoforms and Active Dimers by LY3009120 Leads to Anti-tumor Activities in RAS or BRAF Mutant Cancers

作者：Sheng-Bin Peng, James R. Henry, Michael D. Kaufman, Wei-Ping Lu, Bryan D. Smith, Subha Vogeti, Thomas J. Rutkoski, Scott Wise, Lawrence Chun, Youyan Zhang, Robert Daniel Van Horn, Tinggui Yin, Xiaoyi Zhang, Vipin Yadav, Shih-Hsun Chen, Xueqian Gong, Xiwen Ma, Yue Webster, Sean G. Buchanan, Igor Mochalkin, Lysiane Huber, Lisa M. Kays, Gregory P. Donoho, Jennie Lenora Walgren, Denis McCann, Phenil J. Patel, Ilaria Conti, Gregory D. Plowman, James J. Starling, Daniel Lee Flynn · 发表于：Cancer Cell · 年份：2015 · DOI：10.1016/j.ccell.2015.08.002 · 被引用次数：313 · 研究领域：Melanoma and MAPK Pathways、Protein Kinase Regulation and GTPase Signaling、Cancer Mechanisms and Therapy