Neck circumference: a useful screening tool of cardiovascular risk in children

作者：Odysseas Androutsos, Evangelia Grammatikaki, George Moschonis, E. Roma‐Giannikou, George Panagiotis Chrousos, Yannis Μanios, Christina Kanaka‐Gantenbein · 发表于：Pediatric Obesity · 年份：2012 · DOI：10.1111/j.2047-6310.2012.00052.x · 被引用次数：96 · 研究领域：Diabetes, Cardiovascular Risks, and Lipoproteins、Obesity, Physical Activity, Diet、Statistical Methods in Epidemiology

OBJECTIVE: Early identification of cardiovascular risk factors consists an essential target for public health. The current study aims to examine the association between neck circumference and several cardiovascular risk factors and to compare it with well-established anthropometric indices. METHODS: Demographic, anthropometric (body weight and height, waist, hip and neck circumference [WC, HC and NC, respectively]), biochemical (total cholesterol, high-density lipoprotein [HDL] cholesterol, low-density lipoprotein [LDL] cholesterol, triglycerides [TG], fasting plasma glucose and serum insulin), clinical (pubertal stage, systolic and diastolic blood pressure [SBP and DBP, respectively]) and lifestyle (dietary intake, physical activity level) data were collected from 324 children (51.5% boys; 48.5% girls) aged 9-13 in Greece. Body mass index z-score (BMI z-score), waist-to-hip ratio (WHR), waist-to-height ratio (WHtR), homeostasis model assessment (HOMA-IR), quantitative insulin sensitivity check index (QUICKI) and fasting glucose to insulin ratio (FGIR) were calculated. RESULTS: All indices (BMI z-score, NC, WC, HC, WHR and WHtR) were correlated with SBP, HDL and insulin-related indices (insulin, HOMA-IR, QUICKI and FGIR) and all indices except WHR with TG. LDL was correlated with BMI z-score, WC, WHR and WHtR, whereas DBP was correlated with BMI z-score, WC, HC and WHtR. In multivariate analysis, HDL, TG, SBP, insulin, HOMA-IR, QUICKI and FGIR were associated with all anthrop...