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Venous Serum, Capillary Serum, and Capillary Plasma Compared for Use in Determination of Lactate Dehydrogenase and Aspartate Aminotransferase Activities

作者:R E Haymond, Joseph A. Knight · 发表于:Clinical Chemistry · 年份:1975 · DOI:10.1093/clinchem/21.7.896 · 被引用次数:10 · 研究领域:Metabolism and Genetic Disorders、Renal function and acid-base balance、Erythropoietin and Anemia Treatment

Lactate dehydrogenase and aspartate aminotransferase activities in capillary serum or plasma were significantly greater than in simultaneously assayed venous serum, the greatest differences being between capillary and venous serum. Although some difference is attributable to tissue fluid contributions, platelets seem to account for most of it, with possible small contributions from leukocytes. Capillary tube size and type appear to be important factors. We recommend that when capillary blood is to be used for enzyme assay, it should be processed as plasma.