Integrating Clinical Data into the i2b2 Repository.

作者：Aaron Abend, Dan Housman, Bruce D. Johnson · 发表于：PubMed · 年份：2009 · 被引用次数：15 · 研究领域：Scientific Computing and Data Management

The Clinical Research Chart, developed at the National Center for Biomedical Computing known as i2b2 (Informatics for Integrating Biology and the Bedside) is gaining acceptance as an important addition to NIH’s software to support translational research. The i2b2 platform allows an institution to integrate a wide variety of clinical data sources into a single repository, and it supports the integration of genomic data for clinical and translational research (1). Developing a clinical data repository from disparate data sources is often a bottleneck for translational research programs because the effort requires collaboration among technical personnel from different parts of the organization. The individuals working with the EMR work in one department, those working with claims data work in another, and the systems collecting data from Intensive Care Units, Operating Rooms, and Emergency Rooms are often stand-alone systems each with its own system architecture, database, and administrative policies. Cooperation among the various groups is therefore both administratively and technically challenging.(2) This paper describes our approach to integrating clinical data into the i2b2 repository, including the use of EMR data, the use of medical claims data as a surrogate and supplement for EMR data, and genomic data. The approach uses 3 zones to manage the transformation and integration process. Each zone provides isolation of processes that provide the data from those that use...