Anti-inflammatory and immunosuppressive drugs and reproduction.
作者:Monika Østensen, Munther A. Khamashta, Michael D. Lockshin, Ann L. Parke, Antonio Luca Brucato, Howard Carp, Andrea. Schwartz Doria, Raj Rai, Pier Luigi Meroni, Irene Cetin, Ronald H. W. M. Derksen, Ware D. Branch, Mario Motta, Caroline Gordon, Guillermo Ruiz‐Irastorza, Arsenio Spinillo, DEBORAH M. FRIEDMAN, Rolando Cimaz, Andrew E. Czeizel, Jean Charles Piette, Ricard Cervera, Roger A. Levy, Maurizio Clementi, Sara De Carolis, Michelle Petri, Yehuda Shoenfeld, David Faden, Guido Valesini, Anǵela Tincani · 发表于:Arthritis Research & Therapy · 年份:2006 · DOI:10.1186/ar1957 · 被引用次数:548 · 研究领域:Pregnancy and Medication Impact、Reproductive System and Pregnancy、Pregnancy and preeclampsia studies
Rheumatic diseases in women of childbearing years may necessitate drug treatment during a pregnancy, to control maternal disease activity and to ensure a successful pregnancy outcome. This survey is based on a consensus workshop of international experts discussing effects of anti-inflammatory, immunosuppressive and biological drugs during pregnancy and lactation. In addition, effects of these drugs on male and female fertility and possible long-term effects on infants exposed to drugs antenatally are discussed where data were available. Recommendations for drug treatment during pregnancy and lactation are given.