Interaction of bisbenzimidazole-substituted carbazole derivatives with G-quadruplexes and living cells

作者：Yongbiao Wei, Xin Zhang, Linlin Wang, Ying Liu, Tao Bing, Xiangjun Liu, Dihua Shangguan · 发表于：RSC Advances · 年份：2015 · DOI：10.1039/c5ra11543d · 被引用次数：23 · 研究领域：DNA and Nucleic Acid Chemistry、Advanced biosensing and bioanalysis techniques、RNA Interference and Gene Delivery

Bisbenzimidazole-substituted carbazole derivatives selectively bind to parallel G-quadruplexes. They enter living cells and exhibit different cytotoxicities depending on their side chains.