The eaeB gene of enteropathogenic Escherichia coli is necessary for signal transduction in epithelial cells

作者：Vida Foubister, Ilan Rosenshine, Michael S. Donnenberg, B. Brett Finlay · 发表于：Infection and Immunity · 年份：1994 · DOI：10.1128/iai.62.7.3038-3040.1994 · 被引用次数：138 · 研究领域：Escherichia coli research studies、Bacterial Genetics and Biotechnology、Viral gastroenteritis research and epidemiology

An enteropathogenic Escherichia coli mutant carrying an internal deletion in the eaeB gene (UMD864) was unable to activate epithelial cell signals, including tyrosine phosphorylation, cytoskeletal rearrangements, and the release of inositol phosphates, indicating that the eaeB locus encodes a product that is involved in stimulating signals in epithelial cells.