DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies.

作者：Sakari Knuutila, A-M Björkqvist, Kirsi Autio, Maija Tarkkanen, Maija Wolf, Outi M. Monni, Joanna Szymańska, Marcelo Luis Larramendy, Johanna Tapper, Heini Pere, Wael M. El-Rifai, Samuli Hemmer, Veli-Matti Wasenius, Virve Vidgren, Ying Zhu · 发表于：PubMed · 年份：1998 · 被引用次数：574 · 研究领域：Genomic variations and chromosomal abnormalities、Cancer Genomics and Diagnostics、Cancer-related Molecular Pathways

This review summarizes reports of recurrent DNA sequence copy number amplifications in human neoplasms detected by comparative genomic hybridization. Some of the chromosomal areas with recurrent DNA copy number amplifications (amplicons) of 1p22-p31, 1p32-p36, 1q, 2p13-p16, 2p23-p25, 2q31-q33, 3q, 5p, 6p12-pter, 7p12-p13, 7q11.2, 7q21-q22, 8p11-p12, 8q, 11q13-q14, 12p, 12q13-q21, 13q14, 13q22-qter, 14q13-q21, 15q24-qter, 17p11.2-p12, 17q12-q21, 17q22-qter, 18q, 19p13.2-pter, 19cen-q13.3, 20p11.2-p12, 20q, Xp11.2-p21, and Xp11-q13 and genes therein are presented in more detail. The paper with more than 150 references and two tables can be accessed from our web site http://www.helsinki.fi/lglvwww/CMG.html. The data will be updated biannually until the year 2001.