Cycling cytoplasmic factors that promote mitosis in the cultured 2-cell mouse embryo

作者：Hester P. M. Pratt, Audrey L. Muggleton-Harris · 发表于：Development · 年份：1988 · DOI：10.1242/dev.104.1.115 · 被引用次数：56 · 研究领域：Pluripotent Stem Cells Research、Reproductive Biology and Fertility、Renal and related cancers

A cytoplasmic component(s), previously shown to rescue the 'blocked' 2-cell mouse embryo in vitro, has been demonstrated to peak in activity during the transition between G2 and M phase and decline thereafter. The possible significance of this component(s) in the regulation of cleavage of the cultured mouse embryo is discussed.