Hormonal and type-dependent adhesion of group B streptococci to human vaginal cells

作者：Giuseppe A. Botta · 发表于：Infection and Immunity · 年份：1979 · DOI：10.1128/iai.25.3.1084-1086.1979 · 被引用次数：65 · 研究领域：Neonatal and Maternal Infections、Streptococcal Infections and Treatments、Reproductive tract infections research

Adhesion of group B streptococci to epithelial cells of the human vagina proved to be type dependent and to fluctuate during the menstrual cycle with a maximum near the time of ovulation. Oral contraception completely abolished the observed cyclic changes. Reduced serum levels of luteinizing hormones (less than 5 mIU/ml) and of follicle-stimulating hormone (less than 10 mIU/ml) were associated with a 10-fold reduction in adhesion of B streptococci to vaginal cells.