Comparison of superoxide with other reducing agents in the biological production of hydroxyl radicals

作者：Christine C. Winterbourn · 发表于：Biochemical Journal · 年份：1979 · DOI：10.1042/bj1820625 · 被引用次数：266 · 研究领域：Environmental Toxicology and Ecotoxicology、Advanced oxidation water treatment、Free Radicals and Antioxidants

Iron--EDTA was shown to catalyse OH. production from H2O2 and ascorbate by a mechanism largely independent of superoxide. When ascorbate and superoxide were both present, the ascorbate mechanism was more important than superoxide as a source of OH., and would appear to be more significantly biologically.