The European Centre for Disease Prevention and Control (ECDC) pilot point prevalence survey of healthcare-associated infections and antimicrobial use

作者：Peter Zarb, B. Coignard, Jolanta Griskeviciene, Arno Müller, Vanessa Vankerckhoven, K. Weist, Herman Goossens, Sofie Vaerenberg, Susan Hopkins, Boudewijn Catry, Dominique L. Monnet, Herman Goossens, C. Suetens, Collective National Contact Points for the ECD · 发表于：Eurosurveillance · 年份：2012 · DOI：10.2807/ese.17.46.20316-en · 被引用次数：799 · 研究领域：Antibiotic Use and Resistance、Nosocomial Infections in ICU、Patient Satisfaction in Healthcare

A standardised methodology for a combined point prevalence survey (PPS) on healthcare-associated infections (HAIs) and antimicrobial use in European acute care hospitals developed by the European Centre for Disease Prevention and Control was piloted across Europe. Variables were collected at national, hospital and patient level in 66 hospitals from 23 countries. A patient-based and a unit-based protocol were available. Feasibility was assessed via national and hospital questionnaires. Of 19,888 surveyed patients, 7.1% had an HAI and 34.6% were receiving at least one antimicrobial agent. Prevalence results were highest in intensive care units, with 28.1% patients with HAI, and 61.4% patients with antimicrobial use. Pneumonia and other lower respiratory tract infections (2.0% of patients; 95% confidence interval (CI): 1.8–2.2%) represented the most common type (25.7%) of HAI. Surgical prophylaxis was the indication for 17.3% of used antimicrobials and exceeded one day in 60.7% of cases. Risk factors in the patient-based protocol were provided for 98% or more of the included patients and all were independently associated with both presence of HAI and receiving an antimicrobial agent. The patient-based protocol required more work than the unit-based protocol, but allowed collecting detailed data and analysis of risk factors for HAI and antimicrobial use.