Cadmium-Binding Peptide Induced in Fission Yeast, Schizosaccharomyces pombe

作者：Akira Murasugi, Chiaki Wada, Yukimasa Hayashi · 发表于：The Journal of Biochemistry · 年份：1981 · DOI：10.1093/oxfordjournals.jbchem.a133627 · 被引用次数：100 · 研究领域：Diatoms and Algae Research、Chromium effects and bioremediation、Biotin and Related Studies

When S. pombe is cultured in a medium containing a high concentration of CdCl2 (1 mM), it grows for over 20 h accumulating Cd2+ in the cells. Simultaneously, Cd-binding peptides (Cd-BP1 and -BP2) are synthesized, and accumulated depending on the time after addition of Cd2+ to the culture medium. Apparent molecular weights of Cd-BP1 and -BP2 are 4,000 and 1,800, respectively. Both Cd-BPs are composed of common unit peptides, confirmed by chemical and physicochemical analyses.