Lifetime prevalence and age-of-onset distributions of mental disorders in the World Health Organization's World Mental Health Survey Initiative.

作者：Ronald C. Kessler, Matthias C. Angermeyer, James C. Anthony, Ron de Graaf, Koen Demyttenaere, I. Gasquet, Giovanni de Girolamo, Semyon Gluzman, Oye Gureje, Josep María Haro, Norito Kawakami, Aimée Karam, Daphna Levinson, María Elena Medina Mora, Mark A. Oakley Browne, José Posada‐Villa, Dan J. Stein, Cheuk Him Adley Tsang, Sergio Aguilar‐Gaxiola, Jordi Alonso, Sing Lee, Steven G. Heeringa, Beth‐Ellen Pennell, Patricia A. Berglund, Michael J. Gruber, Maria Petukhova, Somnath Chatterji, T. B. Üstün · 发表于：PubMed · 年份：2007 · 被引用次数：2571 · 研究领域：Mental Health Treatment and Access、Child and Adolescent Psychosocial and Emotional Development、Bipolar Disorder and Treatment

Data are presented on the lifetime prevalence, projected lifetime risk, and age-of-onset distributions of mental disorders in the World Health Organization (WHO)'s World Mental Health (WMH) Surveys. Face-to-face community surveys were conducted in seventeen countries in Africa, Asia, the Americas, Europe, and the Middle East. The combined numbers of respondents were 85,052. Lifetime prevalence, projected lifetime risk, and age of onset of DSM-IV disorders were assessed with the WHO Composite International Diagnostic Interview (CIDI), a fully-structured lay administered diagnostic interview. Survival analysis was used to estimate lifetime risk. Median and inter-quartile range (IQR) of age of onset is very early for some anxiety disorders (7-14, IQR: 8-11) and impulse control disorders (7-15, IQR: 11-12). The age-of-onset distribution is later for mood disorders (29-43, IQR: 35-40), other anxiety disorders (24-50, IQR: 31-41), and substance use disorders (18-29, IQR: 21-26). Median and IQR lifetime prevalence estimates are: anxiety disorders 4.8-31.0% (IQR: 9.9-16.7%), mood disorders 3.3-21.4% (IQR: 9.8-15.8%), impulse control disorders 0.3-25.0% (IQR: 3.1-5.7%), substance use disorders 1.3-15.0% (IQR: 4.8-9.6%), and any disorder 12.0-47.4% (IQR: 18.1-36.1%). Projected lifetime risk is proportionally between 17% and 69% higher than estimated lifetime prevalence (IQR: 28-44%), with the highest ratios in countries exposed to sectarian violence (Israel, Nigeria, and South Africa),...