Genetic Analysis of the System that Reduces Biotin- d -Sulfoxide in Escherichia coli

作者：Daniel E. Dykhuizen · 发表于：Journal of Bacteriology · 年份：1973 · DOI：10.1128/jb.115.2.662-667.1973 · 被引用次数：24 · 研究领域：Biotin and Related Studies、Molecular Junctions and Nanostructures、Click Chemistry and Applications

Four genes of Escherichia coli whose products are needed to reduce biotin-d-sulfoxide to biotin have been mapped: bisA next to chlA, bisB next to chlE, bisC linked to xyl, and bisD next to chlG. A defective lambda transducing phage, lambdadbis5, which carries all the bacterial genes between the lambda attachment site and chlE, was isolated and shown to have lost the phage genes from int through Q.