Long-Term Follow-up of Depressive Pseudodementia of the Aged

作者：Vojtech A. Kral, Olga Beattie Emery · 发表于：The Canadian Journal of Psychiatry · 年份：1989 · DOI：10.1177/070674378903400515 · 被引用次数：185 · 研究领域：CNS Lymphoma Diagnosis and Treatment、Intracerebral and Subarachnoid Hemorrhage Research、Neurological and metabolic disorders

Forty-four elderly patients of both sexes (mean age 76.5 years) suffering from depressive pseudodementia were intensively treated for the depression. When that cleared up, cognitive function reverted to premorbid level. Patients were regularly interviewed and retested at six months intervals for four to 18 years (average 8). Some patients experienced, during the follow-up period, a recurrence of the depression for which they were again successfully treated. At the end of the observation period, 39 of the 44 patients (89%) had developed a dementia syndrome of the Alzheimer type.