Nucleosomes: the structural quantum in chromosomes.

作者：Donald E. Olins, Ada L. Olins · 发表于：PubMed · 年份：1979 · 被引用次数：18 · 研究领域：Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities、Chromosomal and Genetic Variations、Genomics and Chromatin Dynamics

The role of the nucleosome in the packaging of DNA within the cell nucleus is discussed. The DNA of eukaryotic cells is organized into a repeating array of nucleohistone particles called nucleosomes. These chromatin subunits are close-packed into higher-order fibers and are modified during chromosome expression. The structure of the nucleosome is described. Diagrams are included. (RJC)