An unusual response of hamster lymphocytes to PHA.

作者：Noemi Ron, A Laufer, Igal Gery · 发表于：PubMed · 年份：1973 · 被引用次数：14 · 研究领域：Neuropeptides and Animal Physiology、Immune Response and Inflammation、Receptor Mechanisms and Signaling

Lymphocytes from lymph nodes, spleen or thymus of hamsters differ from those of guinea-pig, rat or mouse in their response to PHA by reacting maximally at concentrations 10–50 times higher than those optimal for other rodents. The cells from the other animals were inhibited by the levels optimal for hamster cells. Hamster lymphocytes, however, resembled cells of the other rodents in their dose response to Con A or PWM. The possibility that the particularity in response of hamster cells is related to number and/or distribution of PHA-receptors is discussed.