Regulation of acetone butanol production in batch and continuous cultures of Clostridium acetobutylicum

作者：Frédéric Monot, Jean‐Marc Engasser, Henri Petitdemange · 发表于：Biotechnol. Bioeng. Symp.; (United States) · 年份：1983 · 被引用次数：46 · 研究领域：Biofuel production and bioconversion、Microbial Metabolic Engineering and Bioproduction、Food composition and properties

The influence of pH and glucose concentration in batch and continuous cultures of Clostridium acetobutylicum is examined. At high pH and low glucose concentration only acids are produced. At low pH and high initial or feed glucose concentration, butanol and acetone are the main metabolites produced. According to a detailed kinetic analysis of the different fermentations, solvents are only produced if the concentration of undissociated butyric acid in the medium reaches a critical level. 10 references, 9 figures, 1 table.