THE BEHAVIOR OF AN UNSTABLE RING CHROMOSOME OF DROSOPHILA MELANOGASTER

作者：Claude W Hinton · 发表于：Genetics · 年份：1955 · DOI：10.1093/genetics/40.6.951 · 被引用次数：94 · 研究领域：Plant tissue culture and regeneration

NOTE: Text or symbols not renderable in plain ASCII are indicated by [...]. Abstract is included in .pdf document. The behavior of "Catcheside's ring," an unstable closed-X chromosome [...] of Drosophila melanogaster, has been analyzed with the purpose of identifying the factors controlling the variable-level of [...] instability and of determining the mechanism of [...] elimination. The Y chromosome and the structure of the homologous rod-X chromosome were shown to have no influence on the frequency of [...] elimination. Since no segregating autosomal or sex-linked modifiers could be detected, the primary control of [...] instability must be limited to the [...] chromosome itself. The behavior of unstable small duplications derive from the [...] chromosome suggests that the locus of [...] instability must be in or near the [...] centromere region. The frequency of [...] elimination is directly related to developmental temperature and to age of maternal [...] parents. Certain preliminary results incurred the speculation that a cytoplasmic factor is operative in [...] elimination. Either anaphase lagging or the production of anaphase bridges by the [...] chromosome will account for its loss. The occurrence of [...] derivatives, deficient for either extensive or small euchromatic segments, suggests that anaphase bridges composed of continuous dicentric rings may be formed; however, such bridges do not necessarily constitute the exclusive means of elimination.