Transformation of encapsulated Streptococcus pneumoniae

作者：Janet Yother, Larry S. McDaniel, David E. Briles · 发表于：Journal of Bacteriology · 年份：1986 · DOI：10.1128/jb.168.3.1463-1465.1986 · 被引用次数：103 · 研究领域：Pneumonia and Respiratory Infections、Antibiotic Resistance in Bacteria、Pneumocystis jirovecii pneumonia detection and treatment

We describe the high-efficiency transformation of several virulent, encapsulated isolates of Streptococcus pneumoniae. Transformation was effected by the induction of competence with competence factor and was apparently the result both of inducing noncompetent recipients and overcoming the inhibition imposed by the capsule.