Antibacterial activity of antipsoriatic herbs: Cassia tora, Momordica charantia and Calendula officinalis

作者：T. S. Roopashree, R Dang, Reetu Rani, C. Narendra · 发表于：International journal of applied research in natural products · 年份：2008 · 被引用次数：205 · 研究领域：Phytochemistry and biological activity of medicinal plants、Toxin Mechanisms and Immunotoxins、Ethnobotanical and Medicinal Plants Studies

Summary: In view of increasing resistance to existing antimicrobial agents, herbal drugs are being looked as very importance source for discovery of new agents for treating various ailments related to bacterial infections. Cassia tora , Calendula officinalis and Momordica charantia are well known plants in Asia including India which posses wide range of pharmacological activities. These drugs have been used in India as  folk remedy in the form of decoctions and infusions to treat bacterial infections and also claimed to be an effective against variety of skin conditions like psoriasis, acne, wounds etc. The present investigation was carried out to study the unexplored area of these drugs towards their antibacterial activity with respect to their traditional use as antipsoriatic agents. The herbs were subjected to successive extraction using different solvents and the extracts were subjected to antibacterial evaluation against both gram positive and gram negative organisms by cup plate technique. Among the various extracts, aqueous extracts were found to be more effective against all the bacteria. Staphyllococcus aureus was more susceptible to the aqueous extracts among the tested organisms. Industrial relevance : The selected herbs have been used traditionally for treating skin diseases like psoriasis, for which there is no complete cure till date. Though exact mechanism of these herbs for their effectiveness in psoriasis is not understood, according to American academy of de...